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Our top choices for Isla Santa María hotels

Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very Good, (219 reviews)
"Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. "
Canada
Aly
$158 nightly
The price is $158
Jan 17 - Jan 18
Hotel Ninfa

Hotel La Casa de Judy

Hotel La Casa de Judy
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (161 reviews)
"No view from the room, breakfast is so so"
United States
Wai Shan
$89 nightly
The price is $89
Jan 26 - Jan 27
Hotel La Casa de Judy

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (122 reviews)
"Beautiful property "
Canada
David
$236 nightly
The price is $260
Jan 23 - Jan 24
Blu Galapagos Sustainable Waterfront Lodge

Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (106 reviews)
"Overall excellent choice for a family stay in Puerto Ayora. Rooms are very clean and spacious and short walk to main ferry pier and lots of restaurants and shopping. "
United States
Aaron
$126 nightly
The price is $126
Jan 15 - Jan 16
Maidith Galapagos Inn

Posada del Mar

Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (215 reviews)
"This place is amazing, I only came across the lounge and kitchen on the higher floor on my second day but by far the best room during my trip"
United States
Sharath
$70 nightly
The price is $70
Jan 18 - Jan 19
Posada del Mar

Galapagos Dreams

Galapagos Dreams
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (124 reviews)
"We stayed for 4 days was very good, the breakfast was delicious and also we booked the activities with them, everything was excellent "
United States
esperanza
$53 nightly
The price is $58
Jan 15 - Jan 16
Galapagos Dreams

Capitan Max B&B

Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (205 reviews)
"Clean , friendly staff, accommodating "
United States
Anna
$79 nightly
The price is $79
Jan 15 - Jan 16
Capitan Max B&B

Twin Hotel Galapagos

Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very Good, (44 reviews)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Canada
Chelsea
$71 nightly
The price is $71
Jan 29 - Jan 30
Twin Hotel Galapagos

Hotel Fiesta

Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (387 reviews)
"Perfect place to stay "
United States
Carol
$155 nightly
The price is $155
Jan 16 - Jan 17
Hotel Fiesta

Hotel Palace Galapagos

Hotel Palace Galapagos
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (101 reviews)
"Great little family run hotel. 5 blocks from the main tourist area. Couldn't fault it! "
Ireland
Suzy
$77 nightly
The price is $77
Jan 31 - Feb 1
Hotel Palace Galapagos

White House Galapagos

White House Galapagos
2.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (99 reviews)
"."
Germany
Andrea Christine
$48 nightly
The price is $48
Jan 16 - Jan 17
White House Galapagos

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (271 reviews)
"Wonderful staff, beautiful room, delicious breakfast!"
United States
Ashley
$198 nightly
The price is $218
Jan 15 - Jan 16
Hotel Cucuve

Lava House Hostal

Lava House Hostal
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (53 reviews)
"I stayed here twice. Both times highly satisfactory. Staff was very friendly and accommodatding. The rooms and garden area are in excellent upkeep and pleasant to hang out in hammocks or seating arrangements. The owners are very kind people, who even helped me organize a free ride back to the airport upon my departure (a relative happened to also take a flight off the island). I highly recommend this establishment. "
United States
Irmgard
$124 nightly
The price is $124
Jan 16 - Jan 17
Lava House Hostal

Casa del Lago Lodging House

Casa del Lago Lodging House
2.0 star property
Puerto Ayora
7.8 out of 10, Good, (13 reviews)
"The Tortuga bay suite is right by the street so you hear the street noise until about 10:30pm on workdays and about 11:30pm on a Friday. The air conditioner doesn’t work well. It makes a noise at night and is quite disturbing. With the many mosquitoes, we could not open the windows and it was quite a terrible experience to sleep at night. The soap and shampoo/body wash are diluted. The fridge is incredibly noisy and you cannot sleep with it being on. The plates are dirty and require extra...
United States
Jingyuan
$68 nightly
The price is $68
Feb 2 - Feb 3
Casa del Lago Lodging House

Palo Santo Galapagos Hotel

Palo Santo Galapagos Hotel
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (18 reviews)
"Very attentive staff and large clean room "
United States
Kay
$204 nightly
The price is $224
Jan 15 - Jan 16
Palo Santo Galapagos Hotel

Hotel Flamingo

Hotel Flamingo
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (112 reviews)
"Amazing place to stay!"
United States
Eszter
$151 nightly
The price is $151
Jan 22 - Jan 23
Hotel Flamingo

Hostal Casa Cascada

Hostal Casa Cascada
2.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (4 reviews)
"I had a great time at this hostel. The owners were committed in making my trip wonderful. "
United States
Jefferson
$45 nightly
The price is $45
Jan 31 - Feb 1
Hostal Casa Cascada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Isla Santa María attractions

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

The circle of life. A sea lion napping near a washed up whale skeleton. The best way to see the Galapagos is island hopping on a cruise ship.  #LifeAtExpedia
Photo by Delen Wong
Open Photo by Delen Wong

Top Isla Santa María Hotel Reviews

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Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Hotel el descanso del Guia and Capitan Max B&B. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home rental near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
Where can I learn more about changing or cancelling my trip to Isla Santa María?
For more details about updating your trip to Isla Santa María or cancelling it, click here.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 209 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.